NAD+
The cell’s main energy-transfer molecule, which falls with age; taken by injection, IV or as oral precursors (NR, NMN).
A coenzyme, not a peptide; injectable NAD+ is compounded.
Used for
- Energy and fatigue
- Healthy aging
- Recovery (IV clinics)
How it works
Needed for making ATP and for sirtuins and DNA repair enzymes. Injected NAD+ is broken down quickly into precursors that cells then take up.
What the research shows
- In a 6-hour IV infusion study, NAD+ vanished from the blood for the first 2 hours as it was broken down.
- Oral nicotinamide riboside raised blood NAD+ in older adults and was well tolerated; clinical benefits are still unproven.
Dosing
Dosing isn’t listed on the public site. In the app, each published option is shown with its source (a drug label, a clinical guideline, a trial or community reports) and can be turned into a protocol you review.
Work out the units to draw for your vial →Side effects
- Flushing, chest tightness, nausea, cramps (worse when given fast)
- Stinging injection
Cautions
- Theoretical concern with cancer (tumors also use NAD+).
Storage
Unmixed powder: freezer or fridge, away from light.
Once mixed with bacteriostatic water: fridge; the common rule is to use it within 28 days.
There is no label or published stability data for this one, so treat these as habits, not limits.
Stability once mixed
It breaks down in water (hydrolysis), faster with warmth and light. Keep it cold and dark.
Heat, shaking, freezing a mixed vial, light and many needle punctures all speed breakdown. Toss it if it turns cloudy, grows specks or changes color.
More in Mitochondria & aging
Reference only, not medical advice. Written for this app from the cited research. Doses marked community-reported are not from trials.