FOXO4-DRI
A designed peptide that makes senescent (“zombie”) cells self-destruct: a senolytic.
Not approved for human use; sold as a research chemical.
Used for
- Clearing senescent cells in aging
How it works
Blocks FOXO4 from holding p53 in senescent cells, so p53 triggers their programmed death while normal cells are spared.
What the research shows
- In fast-aging and naturally old mice it restored fitness, fur and kidney function (Baar 2017). No human data.
Dosing
Dosing isn’t listed on the public site. In the app, each published option is shown with its source (a drug label, a clinical guideline, a trial or community reports) and can be turned into a protocol you review.
Work out the units to draw for your vial →Side effects
- Unknown in people
Cautions
- No human safety data at all.
- Research-chemical vials have no quality control: purity, dose and sterility vary. Third-party testing helps but is no guarantee.
Storage
Unmixed powder: freezer or fridge, away from light.
Once mixed with bacteriostatic water: fridge; the common rule is to use it within 28 days.
There is no label or published stability data for this one, so treat these as habits, not limits.
More in Mitochondria & aging
Reference only, not medical advice. Written for this app from the cited research. Doses marked community-reported are not from trials.