Ipamorelin
A ghrelin-mimicking peptide that releases GH with little effect on cortisol, prolactin or appetite.
Investigational (reached phase 2 for post-surgery gut recovery); not approved.
Used for
- Pulsed GH release, usually with CJC-1295 / Mod GRF
- Sleep, recovery, body composition
How it works
Activates the ghrelin (GHS) receptor on the pituitary. Unlike GHRP-2 and GHRP-6 it barely raises cortisol or prolactin, even at high doses.
Half-life: about 2 hours
What the research shows
- Its selectivity was shown in animals (Raun 1998).
- It was tested in people for gut recovery after bowel surgery and failed to beat placebo; no trials for body composition.
Dosing
Dosing isn’t listed on the public site. In the app, each published option is shown with its source (a drug label, a clinical guideline, a trial or community reports) and can be turned into a protocol you review.
Work out the units to draw for your vial →Side effects
- Head rush or flushing
- Mild hunger, water retention
- Vivid dreams
Cautions
- Raises GH and IGF-1. Avoid with active cancer or a history of it; can raise blood sugar. Check IGF-1 and fasting glucose on bloodwork.
- Prohibited in tested sports (WADA).
- Research-chemical vials have no quality control: purity, dose and sterility vary. Third-party testing helps but is no guarantee.
Storage
Unmixed powder: freezer or fridge, away from light.
Once mixed with bacteriostatic water: fridge; the common rule is to use it within 28 days.
There is no label or published stability data for this one, so treat these as habits, not limits.
Stability once mixed
No stability data. A short chain without obvious weak spots; community reports of 4 weeks or more in the fridge, untested.
Heat, shaking, freezing a mixed vial, light and many needle punctures all speed breakdown. Toss it if it turns cloudy, grows specks or changes color.
More in Growth hormone
Reference only, not medical advice. Written for this app from the cited research. Doses marked community-reported are not from trials.