TB-500 (thymosin beta-4)
Sold as a synthetic version or fragment of thymosin beta-4, a protein that helps cells move to and rebuild injured tissue.
Not approved for human use; sold as a research chemical.
Used for
- Soft-tissue injuries, often stacked with BPC-157 ("Wolverine stack")
- Flexibility and recovery
- Wound healing
How it works
Thymosin beta-4 binds actin, the protein cells use to move, which helps repair cells migrate into a wound; it also dampens inflammation and supports new blood vessels.
What the research shows
- The human trials are of full thymosin beta-4 as eye drops or skin gel, not of injected TB-500.
- A phase 2 trial of 0.1% thymosin beta-4 eye drops improved dry-eye signs and symptoms over 28 days with no adverse events.
- Injected TB-500 dosing comes from veterinary (racehorse) and community use; no human injection trials.
Dosing
Dosing isn’t listed on the public site. In the app, each published option is shown with its source (a drug label, a clinical guideline, a trial or community reports) and can be turned into a protocol you review.
Work out the units to draw for your vial →Side effects
- Tiredness or head rush after a dose
- Injection-site irritation
Cautions
- Supports cell migration and blood vessel growth: avoid with active cancer.
- Prohibited in tested sports (WADA).
- Research-chemical vials have no quality control: purity, dose and sterility vary. Third-party testing helps but is no guarantee.
Storage
Unmixed powder: freezer or fridge, away from light.
Once mixed with bacteriostatic water: fridge; the common rule is to use it within 28 days.
There is no label or published stability data for this one, so treat these as habits, not limits.
Stability once mixed
No stability data. A longer chain than most, with no obvious weak spot; community reports of 4 weeks or more in the fridge, untested.
Heat, shaking, freezing a mixed vial, light and many needle punctures all speed breakdown. Toss it if it turns cloudy, grows specks or changes color.
Reference only, not medical advice. Written for this app from the cited research. Doses marked community-reported are not from trials.