KPV
The last three amino acids of alpha-MSH (Lys-Pro-Val), studied as an anti-inflammatory for the gut and skin.
Not approved for human use; sold as a research chemical.
Used for
- Gut inflammation: colitis, IBD symptoms
- Skin inflammation
- Often combined with BPC-157 and GHK-Cu in blends
How it works
Enters gut-lining and immune cells through the PepT1 transporter and blocks NF-κB, a switch for inflammatory signals. It does not tan the skin like the full hormone.
What the research shows
- In mice, oral KPV reduced colitis through PepT1 uptake.
- Colon-targeted nanoparticles carrying KPV reduced colitis in mice.
- No human trials.
Dosing
Dosing isn’t listed on the public site. In the app, each published option is shown with its source (a drug label, a clinical guideline, a trial or community reports) and can be turned into a protocol you review.
Work out the units to draw for your vial →Side effects
- Few reported
Cautions
- Research-chemical vials have no quality control: purity, dose and sterility vary. Third-party testing helps but is no guarantee.
Storage
Unmixed powder: freezer or fridge, away from light.
Once mixed with bacteriostatic water: fridge; the common rule is to use it within 28 days.
There is no label or published stability data for this one, so treat these as habits, not limits.
More in Healing & recovery
Reference only, not medical advice. Written for this app from the cited research. Doses marked community-reported are not from trials.