Semax
A nasal peptide built from a fragment of ACTH, used for focus, memory and stroke recovery.
Approved in Russia (nasal drops) for stroke and cognitive problems; not approved elsewhere.
Used for
- Focus and mental energy
- Stroke recovery (Russia)
- Brain fog
How it works
Raises BDNF and its receptor in the brain and affects dopamine and serotonin, without ACTH’s hormonal effects.
What the research shows
- Rat studies show more BDNF in the hippocampus and gene changes after brain ischemia.
- Human trials are Russian and mostly not in English; no large Western trials.
Dosing
Dosing isn’t listed on the public site. In the app, each published option is shown with its source (a drug label, a clinical guideline, a trial or community reports) and can be turned into a protocol you review.
Work out the units to draw for your vial →Side effects
- Nasal irritation
- Overstimulation, irritability or poor sleep if taken late
Cautions
- Research-chemical vials have no quality control: purity, dose and sterility vary. Third-party testing helps but is no guarantee.
Storage
Unmixed powder: freezer or fridge, away from light.
Once mixed with bacteriostatic water: fridge; the common rule is to use it within 28 days.
There is no label or published stability data for this one, so treat these as habits, not limits.
Reference only, not medical advice. Written for this app from the cited research. Doses marked community-reported are not from trials.